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As for alcohol and cannabis, cannabis doesnt have that much effect on the CNS, but as with any mixture of drugs it becomes harder and harder for the body to cope.
Also cannabis seems to make the stomach lighter and your more likely to be sick, and if you've passed out thats VERY dangerous.
CBD is a narcotic and will have sedative effects.
And as for being economic development being a factor, the countries with the poorest populations are quite often the ones most ravaged by drug use.
I do see what you mean though, although i think in LEDCs people tend to work more hence drink less, and if families are poorer they may have no money to spend on alcohol as it is. Although quite a week theory, but if you look at the locals in tourist countries like Portugal, you rarely see them drinking.