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Want it, can't have it?

So being a student, having a 'social life' mainly consists of going out and getting drunk, socials tend to be food and alcohol related, tell me a social you have had at Uni that doesn't consist of either of them? When I originally started drinking, I used to get completely off my head drunk, to the point, I would attack people, scream, melt down, but I found that was down to mixing medication with alcohol. Since I stopped doing that, I found I could have a really good night and not melt down, I was lively, bubbly, and far to talkative. I used to be able to jug down pitcher after pitcher really, most night, I could go through 7-8 cocktails and not be that drunk, just really loud, but nowadays, it's almost as though my body hates it, and I don't get why, I can have a 1/4 of a glass, and feel absolutely horrendous. My eyes would go pretty red quite quickly, my heart rate would speed up, I would get light headed and all that m'larkey and I would feel horrendous the next morning (Hence the reason I'm still lying in bed). What I don't get is, why? I love going out with my friends, and nowadays, mocktails are my only option. But what's wrong with me? Why can I no longer handle alcohol? Its not like I've been drinking it that long or nowt?
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Meds have been changed around a bit, but I don't tend to take them when I know I'm going out for drinks. My diets changed immensly, cause Vegan now, don't need cruelty in my food or nowt! - But like it wouldn't stop me being able to completly drinking alcohol though? Like I legit can only manage 1/4 of a glass and feel pukey, and feel dreadful the next day, my eyes go red quite quickly too, like I don't even know why?
Your body may also have lost the ability to process it, if you've overdone it in the past?