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HELP!!! drugs not working anymore!!!

Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
hi there. my name is shawn and i am 27 years old. i have been having a problem recently with my medications not working at all. i take cymbalta 60mg 1x daily, zantac 150mg 2x daily, endocet (percocet) 10/325mg 3x daily, ambien 10mg 1x at night and resperidone 3mg 1x at night. for some time now my endocet simply has not been working. i have also tried taking some adderol 20mg for a while and it had no effect either. im thinking it may have something to do with the fact that i abused tramadol for about 5 months straight. i would take about 14 50mg pills a day to try and treat my pain.... ive been off of it for atleast 3 months now and it seems to have affected my brain chemically. i either have a developed an extremely high tolerance or im thinking i might have just depleted my dopamine to a degree in which medications wont work anymore... please help me figure this out because it is driving me absolutely nuts. i will check this topic frequently to answer any questions you guys may have for me. any input you have for me is welcome... so post away. my sincere thanks....

Comments

  • Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
    Have you spoken to the medical professional who prescribes your medication?
  • Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
    With that level of medication you should be seeing a pain specialist.
  • Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
    with those sort of dosages, i would say you have definitely built up a very high tolerance, or even immunity to those drugs. even without having abused tramadol, you may have developed this tolerance,just maybe not as quickly. definitely speak to your doctor.. they may need to prescribe something stronger, or a medication with a different composition.. this would bypass your tolerance, and still be effective
  • Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
    ok thanks

    thank you for the input. i actually do see a pain specialist and that is all he will prescribe for me... so im kinda SOL... but ill keep asking him for something stronger.
  • Former MemberFormer Member Posts: 1,876,324 The Mix Honorary Guru
    tell him it doesnt work anymore.. something stronger will only increase your immunity. you need something with a completely different composition, because your body wont have a tolerance for it
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