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Neurotoxicity
BillieTheBot
Posts: 8,721 Bot
Neurotoxicity (often referred to as 'brain damage') due to Ecstasy.
The widely publicised claim that Ecstasy causes neurodegeneration or brain damage (which might result in long term problems such as depression or even Parkinson's Disease) is based on animal experiments, most of them carried out by Ricaurte and McCann. Since counting damaged neurons is impractical, they used indirect methods which are disputed by other experts, in particular O'Callaghan of the US Environmental Protection Agency.
O'Callaghan was given a $750,000 commission to find the most accurate method for assaying neurotoxicity in humans. He came up with a procedure called Reactive Gliosis which shows that Methamphetamine, Ecstasy and fenfluramine are not neurotoxic. His findings pleased the French drug company Servier who wanted to market fenfluramine in the USA, and this year the US Food and Drug Administration called both O'Callaghan and Ricaurte as expert witnesses to decide whether fenfluramine was safe. Ricaurte's research shows that both Ecstasy and fenfluramine are identically neurotoxic and therefore fenfluramine should not be released. But the expert committee took O'Callaghan's view and decided to grant unlimited use on the grounds that the benefits of fenfluramine outweigh the possible risks... It is a slimming pill.
Info taken from Ecstasy.org.
Does that take the piss or what!
The ability to lose weight outways the risks. Can't be that risky then can it.
Forwards ever, Backwards never - Skive
[This message has been edited by Skive'n'Dive (edited 24-06-2001).]
The widely publicised claim that Ecstasy causes neurodegeneration or brain damage (which might result in long term problems such as depression or even Parkinson's Disease) is based on animal experiments, most of them carried out by Ricaurte and McCann. Since counting damaged neurons is impractical, they used indirect methods which are disputed by other experts, in particular O'Callaghan of the US Environmental Protection Agency.
O'Callaghan was given a $750,000 commission to find the most accurate method for assaying neurotoxicity in humans. He came up with a procedure called Reactive Gliosis which shows that Methamphetamine, Ecstasy and fenfluramine are not neurotoxic. His findings pleased the French drug company Servier who wanted to market fenfluramine in the USA, and this year the US Food and Drug Administration called both O'Callaghan and Ricaurte as expert witnesses to decide whether fenfluramine was safe. Ricaurte's research shows that both Ecstasy and fenfluramine are identically neurotoxic and therefore fenfluramine should not be released. But the expert committee took O'Callaghan's view and decided to grant unlimited use on the grounds that the benefits of fenfluramine outweigh the possible risks... It is a slimming pill.
Info taken from Ecstasy.org.
Does that take the piss or what!
The ability to lose weight outways the risks. Can't be that risky then can it.
Forwards ever, Backwards never - Skive
[This message has been edited by Skive'n'Dive (edited 24-06-2001).]
Beep boop. I'm a bot.
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